The USA never claimed victory on the evening thanks to Gareth Bale’s penalty kick in the 82nd minute.
With a calm finish in the 36th minute, Timothy Weah, the son of former World Footballer of the Year George Weah, gave the Americans the lead.
Christian Pulisic of Chelsea earned credit for the goal by setting up Weah, who shot past the Welsh goalkeeper with ease.
The USA had several chances to put the game away in the second half, but none of them were successful.
When Walker Zimmerman ran over Welsh star Gareth Bale from behind with Bale’s back to the goal in the final 10 minutes, referee Abdulrahman Al-Jassim of host Qatar pointed to the penalty spot.
In his 41st goal in 109 international games, Bale cornered the ball to the left of goalkeeper Matt Turner’s extended arm, giving Wales a point in their first World Cup game since 1958.
Wales and the USA split the wins in the tournament’s opening tie, keeping pace with leaders England by two points.